Construction of Genetically Encoded Light-Up RNA Aptamers for Label-free and Ultrasensitive Detection of CircRNAs in Cancer Cells and Tissues.
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DOI: 10.1021/acs.analchem.3c01624
Abstract: Circular RNAs (circRNAs) as endogenous non-coding RNAs are characterized by covalently closed circular structures, and they widely exist in mammalian cells. The aberrant expression of circRNAs may result in various diseases. Herein, we demonstrate the… read more here.
Keywords: construction genetically; light rna; rna aptamers; detection ... See more keywords