Recent advances in electrochemically enabled construction of indoles from non-indole-based substrates.
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DOI: 10.1039/d4cc03040k
Abstract: Indole motifs are important heterocycles found in natural products, pharmaceuticals, agricultural chemicals, and materials. Although there are well-established classical name reactions for indole synthesis, these transformations often require harsh reaction conditions, have a limited substrate… read more here.
Keywords: indole based; synthesis; non indole; based substrates ... See more keywords
Iron-Promoted Construction of Indoles via Intramolecular Oxidative C–N Coupling of 2-Alkenylanilines Using Persulfate
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DOI: 10.1055/s-0037-1611521
Abstract: Indole scaffold synthesis relies primarily on oxidative C–H amination of N-protected alkenylanilines for C–N intramolecular cyclization reactions. Herein, for the first time, without N-protection, various readily prepared 2-alkenylanilines were transformed into the desired indole products… read more here.
Keywords: iron promoted; construction indoles; via intramolecular; indoles via ... See more keywords