Organocatalytic Enantioselective Construction of Spiroketal Lactones Bearing Axial and Central Chirality via an Asymmetric Domino Reaction.
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DOI: 10.1021/acs.orglett.2c00845
Abstract: The catalytic asymmetric synthesis of chiral compounds with multiple stereogenic elements via a single catalytic process is challenging. This paper proposes a domino asymmetric electrophilic halocyclization strategy for constructing heterocycloalkenyl atropisomeric spiroketal lactones. A single… read more here.
Keywords: spiroketal lactones; construction spiroketal; enantioselective construction; domino ... See more keywords