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Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-125175
Abstract: The epichaperome, which was previously described by our team (Rodina et al. Nature 2016, Joshi et al. Nature Reviews Cancer 2018), is a complex hyper-connected network of chaperones and co-chaperones that are present in a…
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-134563
Abstract: Introduction Major thalassemia (TM) and sickle cell disease (SCD), two common genetic hemoglobinopathies, were often fatal 50 years ago. Novel therapeutic and diagnostic methods are increasing lifespan and quality of life. Recent advances in iron…
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-136791
Abstract: Leukemic blasts and stem cells in AML express high levels of CD123 compared to normal hematopoietic stem and progenitor cells, making CD123 a potential therapeutic target (Kovtun, Blood advances, 2018). IMGN632, a novel CD123-targeting ADC…
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-142818
Abstract: Introduction:Adult T cell Leukemia/Lymphoma (ATLL) is a mature T-Cell-neoplasm related to human T-cell lymphotropic virus type 1 (HTLV-1) infection that shows variable clinical presentation and adverse prognosis with shorter overall survival (OS) when compared to…
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Published in 2021 at "Blood"
DOI: 10.1182/blood-2021-152948
Abstract: BACKGROUND AND AIMS Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder causing low platelet counts (PC) and increased bleeding. COVID-19 vaccines are a major concern for ITP patients who fear vaccination might exacerbate their thrombocytopenia.…
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entity board;
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