Plasma contact factors as therapeutic targets.
Sign Up to like & getrecommendations! Published in 2018 at "Blood reviews"
DOI: 10.1016/j.blre.2018.04.001
Abstract: Direct oral anticoagulants (DOACs) are small molecule inhibitors of the coagulation proteases thrombin and factor Xa that demonstrate comparable efficacy to warfarin for several common indications, while causing less serious bleeding. However, because their targets… read more here.
Keywords: therapeutic targets; contact factors; factors therapeutic; plasma contact ... See more keywords
Factors determining human-to-human transmissibility of zoonotic pathogens via contact
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DOI: 10.1016/j.coviro.2016.11.004
Abstract: The pandemic potential of zoonotic pathogens lies in their ability to become efficiently transmissible amongst humans. Here, we focus on contact-transmitted pathogens and discuss the factors, at the pathogen, host and environmental levels that promote… read more here.
Keywords: human transmissibility; contact factors; zoonotic pathogens; contact ... See more keywords