Articles with "contact residues" as a keyword



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Location of contact residues in pharmacologically distinct drug binding sites on P‐glycoprotein

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Published in 2017 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2016.10.002

Abstract: Graphical abstract Figure. No Caption available. Abstract The multidrug resistance P‐glycoprotein (P‐gp) is characterised by the ability to bind and/or transport an astonishing array of drugs. This poly‐specificity is imparted by at least four pharmacologically… read more here.

Keywords: drug binding; central cavity; contact residues; pharmacologically distinct ... See more keywords