Chromosome contacts in activated T cells identify autoimmune disease candidate genes
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DOI: 10.1186/s13059-017-1285-0
Abstract: BackgroundAutoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4+ T cells. Linking such regulatory regions to gene promoters in disease-relevant cell contexts facilitates identification of candidate disease genes.ResultsWithin 4 h, activation… read more here.
Keywords: candidate; disease; contacts activated; activated cells ... See more keywords