Synthesis and Biological Evaluation of Selenium-Containing 4-Anilinoquinazoline Derivatives as Novel Antimitotic Agents.
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DOI: 10.1021/acs.jmedchem.8b00128
Abstract: Twenty-eight novel selenium-containing 4-anilinoquinazoline derivatives were designed, synthesized, and evaluated as antiproliferative agents. Most of them had significant in vitro activities, particularly for compounds 23a, 25a, and 25d, which also exhibited the most potent antitumor… read more here.
Keywords: selenium containing; 23a 25a; 25a 25d; containing anilinoquinazoline ... See more keywords