Overall Shape Constraint of Alternating α/β-Hybrid Peptides Containing Bicyclic β-Proline.
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DOI: 10.1021/acs.orglett.9b02799
Abstract: Our NMR, IR/Raman, CD spectroscopic, and X-ray crystallographic studies, as well as accelerated molecular dynamics simulations, showed that alternating hybrid α/β-peptides containing a bicyclic β-proline surrogate form unique extended curved folds, regardless of the peptide… read more here.
Keywords: alternating hybrid; bicyclic proline; containing bicyclic; peptides containing ... See more keywords