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Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03603
Abstract: We present herein a visible-light-induced [3 + 2] cycloaddition of a hypervalent iodine(III) reagent with α-ketoacids for the construction of 5-CF3-1,3,4-oxadiazoles that are of importance in medicinal chemistry. The reaction proceeds smoothly without a photocatalyst,…
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Keywords:
cycloaddition;
building block;
containing building;
cf3 ... See more keywords