Developing a Targeted Quantitative Strategy for Sulfoxide-Containing MS-Cleavable Cross-Linked Peptides to Probe Conformational Dynamics of Protein Complexes.
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DOI: 10.1021/acs.analchem.1c05298
Abstract: In recent years, cross-linking mass spectrometry (XL-MS) has made enormous strides as a technology for probing protein-protein interactions (PPIs) and elucidating architectures of multisubunit assemblies. To define conformational and interaction dynamics of protein complexes under… read more here.
Keywords: cleavable cross; protein complexes; containing cleavable; cross ... See more keywords