4‐Fluorobenzylpiperazine‐Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase
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DOI: 10.1002/cmdc.202000125
Abstract: Tyrosinase is a type‐3 copper protein involved in the biosynthesis of melanin pigments; therefore, the inhibition of its enzymatic activity represents a promising strategy for the treatment of hyperpigmentation‐related disorders. To address this point, we… read more here.
Keywords: derivatives efficient; containing derivatives; fluorobenzylpiperazine containing; tyrosinase ... See more keywords
A [15]paracyclophenone and its fluorenone-containing derivatives: syntheses and binding to nerve agent mimics via aryl-CH hydrogen bonding interactions
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DOI: 10.1039/d0qo00456a
Abstract: The syntheses and crystal structures of a [15]paracyclophenone and its two fluorenone-containing derivatives I and II are reported. The nerve agent mimics binding behaviors with 2 and I driven by the ‘non-traditional’ aryl-CH hydrogen bonding… read more here.
Keywords: aryl hydrogen; agent mimics; containing derivatives; fluorenone containing ... See more keywords