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Published in 2019 at "International immunology"
DOI: 10.1093/intimm/dxz077
Abstract: Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory disease. IQ motif-containing GTPase-activating protein 1 (IQGAP1) is a ubiquitously expressed scaffold…
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Keywords:
lung ilc2s;
containing gtpase;
gtpase activating;
ilc2s ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.920652
Abstract: IQ motif-containing GTPase-activating proteins (IQGAPs) are a class of scaffolding proteins, including IQGAP1, IQGAP2, and IQGAP3, which govern multiple cellular activities by facilitating cytoskeletal remodeling and cellular signal transduction. The role of IQGAPs in cancer…
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Keywords:
hepatocellular carcinoma;
activating proteins;
role;
motif containing ... See more keywords