Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra07056a
Abstract: 2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics, and remarkable physicochemical properties such as metabolic stability, solubility in water, and lipophilicity.… read more here.
Keywords: multicomponent reactions; pyridone containing; pyridone; bioactive pyridone ... See more keywords
Research Progress and Prospect of Nitrogen-containing Heterocycle in Anti-gastric Cancer Drugs: A Review.
Sign Up to like & getrecommendations! Published in 2024 at "Current medicinal chemistry"
DOI: 10.2174/0109298673296147240405113328
Abstract: Gastric cancer was the fifth most common cancer, and its drug treatment mainly included chemotherapy, targeted therapy, and immunotherapy. With the rise of immunotherapy in gastric cancer, small-molecule anti-gastric cancer drugs still have irreplaceable places… read more here.
Keywords: cancer; containing heterocycle; heterocycle; gastric cancer ... See more keywords