Chemoenzymatic Synthesis of O‐Containing Heterocycles from α‐Diazo Esters
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201901602
Abstract: The synergy of biocatalysis and transition metal catalysis is rapidly moving forward, providing increasingly effective workflows in chemical synthesis. Here we present a facile way to prepare synthetically challenging O‐containing heterocycles bearing disubstituted stereogenic centers… read more here.
Keywords: heterocycles diazo; synthesis containing; diazo esters; chemoenzymatic synthesis ... See more keywords
Recent Advances in Organic Photovoltaic Materials Based on Thiazole-Containing Heterocycles.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202300102
Abstract: Organic solar cells (OSCs) have achieved great progress driven by the rapid development of wide bandgap electron donors and narrow bandgap non-fullerene acceptors (NFAs). Among large amount of electron-accepting (A) building blocks, thiazole (Tz) and… read more here.
Keywords: materials based; photovoltaic materials; advances organic; organic photovoltaic ... See more keywords
SELENIUM DIHALIDES: NEW POSSIBILITIES FOR THE SYNTHESIS OF SELENIUM-CONTAINING HETEROCYCLES
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DOI: 10.1007/3569
Abstract: This microreview is devoted to methods for the synthesis of selenium-containing heterocycles on the basis of new electrophilic reagents – selenium dihalides. Authors: M. V. Musalov , V. A. Potapov read more here.
Keywords: selenium containing; dihalides new; synthesis selenium; selenium dihalides ... See more keywords
THE EFFECT OF THE STRUCTURE OF DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLES ON THEIR ANTI-INFLUENZA ACTIVITY
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5020
Abstract: Для оптимизации поиска новых противогриппозных агентов была построена вполне адекватная модель QSAR на базе симплексного представления молекулярной структуры. Структурная интерпретация модели позволила выявить молекулярные фрагменты, определяющие активность соединений против вирусов гриппа человека. Проведенный в дальнейшем… read more here.
Keywords: structure derivatives; effect structure; nitrogen containing; heterocycles anti ... See more keywords
SATURATED SPIROCYCLIC NITROGEN-CONTAINING HETEROCYCLES WITH gem -DIFLUOROCYCLOALKANE MOIETIES
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5091
Abstract: Recent advances in synthetic and medicinal chemistry of saturated spirocyclic nitrogen-containing heterocycles with gem-difluorocycloalkane moieties are surveyed, including results published in the last decade. In particular, gem-difluoro-substituted derivatives of azaspiro[2.n]alkanes, azaspiro[3.n]alkanes, azaspiro[4.5]decane, and other spirocyclic… read more here.
Keywords: heterocycles gem; saturated spirocyclic; spirocyclic nitrogen; chemistry ... See more keywords
Isatin containing heterocycles for different biological activities: Analysis of structure activity relationship
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128900
Abstract: Abstract Isatin has been widely used in drug discovery. The ring is part of many naturally occurring compounds and is used to design compounds with diverse biological activities. These isatin containing heterocycles are active and… read more here.
Keywords: isatin containing; isatin; biological activities; structure ... See more keywords
Regio- and chemoselective synthesis of nitrogen-containing heterocycles via the oxidative cascade cyclization of unactivated 1,n-enynes.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/c9cc07820g
Abstract: The development of a method for performing radical initiated intramolecular cascade cyclization of 1,n-enynes provided a competent protocol for producing structurally diverse complex heterocycles. Herein, we demonstrate I2/TBHP promoted, solvent controlled, regio- and chemoselective 5-exo-trig… read more here.
Keywords: cascade cyclization; cyclization; nitrogen containing; regio chemoselective ... See more keywords
Cobalt-catalyzed synthesis of N-containing heterocycles via cyclization of ortho-substituted anilines with CO2/H2
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DOI: 10.1039/c9gc00095j
Abstract: The CO2-involved synthesis of chemicals is of great significance from the green and sustainable chemistry viewpoint. read more here.
Keywords: synthesis; cobalt catalyzed; chemistry; catalyzed synthesis ... See more keywords
Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions
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DOI: 10.1039/d2ra07056a
Abstract: 2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics, and remarkable physicochemical properties such as metabolic stability, solubility in water, and lipophilicity.… read more here.
Keywords: multicomponent reactions; pyridone containing; pyridone; bioactive pyridone ... See more keywords
Construction of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides and derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00836c
Abstract: Recent advances in the direct synthesis of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides (TFAICs) and derivatives, including trifluoroacetimidohydrazides (TFAIHs) and CF3-imidoyl sulfoxonium ylides (TFISYs), are systematically summarized and discussed. The cascade annulation reactions of trifluoromethyl-containing synthons… read more here.
Keywords: heterocycles trifluoroacetimidoyl; trifluoromethyl containing; construction trifluoromethyl; trifluoroacetimidoyl chlorides ... See more keywords
Synthesis of trifluoromethyl N,N-aminals from nitrogen containing heterocycles by using a plasma flow microreactor.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00942d
Abstract: Trifluoromethyl N,N-aminals are important precursors allowing access to fluorinated building blocks. In this work, the direct synthesis of trifluoromethyl N,N-aminals from nitrogen containing heterocycles is reported using argon plasma in a continuous flow microreactor without… read more here.
Keywords: synthesis trifluoromethyl; trifluoromethyl; aminals nitrogen; nitrogen containing ... See more keywords