Novel thiosemicarbazone derivatives containing indole fragment as potent and selective anticancer agent.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111764
Abstract: Potent and safe anticancer drugs research and development are still on the way to human health. In this report, a series of novel thiosemicarbazone derivatives containing indole fragment were designed and synthesized. Most compounds exhibited… read more here.
Keywords: novel thiosemicarbazone; indole fragment; thiosemicarbazone derivatives; derivatives containing ... See more keywords
Significant anti-inflammatory aziridine-containing indole alkaloids from the Chinese medicinal plant Alstonia scholaris.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc07029d
Abstract: Two unique windmill-like aziridine-containing indole alkaloids, possessing an unprecedented 6/5/5/6/6/5/3 rigid ring system and an unusual azabicyclo[3.1.0]hexane core, were isolated from Alstonia scholaris. Their structures were established by spectroscopy, X-ray diffraction, and electronic circular dichroism… read more here.
Keywords: containing indole; indole alkaloids; anti inflammatory; alstonia scholaris ... See more keywords