Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2017.07.023
Abstract: Summary Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases. To date, it… read more here.
Keywords: fast spiking; properties fast; neurons properties; spiking parvalbumin ... See more keywords
Functional Differentiation of Cholecystokinin‐Containing Interneurons Destined for the Cerebral Cortex
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DOI: 10.1093/cercor/bhw094
Abstract: Abstract Although extensively studied postnatally, the functional differentiation of cholecystokinin (CCK)‐containing interneurons en route towards the cerebral cortex during fetal development is incompletely understood. Here, we used CCKBAC/DsRed mice encoding a CCK promoter‐driven red fluorescent… read more here.
Keywords: cerebral cortex; differentiation cholecystokinin; functional differentiation; embryonic day ... See more keywords
Somatostatin and Somatostatin-Containing Interneurons—From Plasticity to Pathology
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020312
Abstract: Despite the obvious differences in the pathophysiology of distinct neuropsychiatric diseases or neurodegenerative disorders, some of them share some general but pivotal mechanisms, one of which is the disruption of excitation/inhibition balance. Such an imbalance… read more here.
Keywords: containing interneurons; brain; plasticity; pathology ... See more keywords