Inhalable particles containing isoniazid and rifabutin as adjunct therapy for safe, efficacious and relapse-free cure of experimental animal tuberculosis in one month.
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DOI: 10.1016/j.tube.2021.102081
Abstract: We investigated the preclinical efficacy and safety/tolerability of biodegradable polymeric particles containing isoniazid (INH) and rifabutin (RFB) dry powder for inhalation (DPI) as an adjunct to oral first-line therapy. Mice and guinea pigs infected with… read more here.
Keywords: free cure; relapse free; tuberculosis; containing isoniazid ... See more keywords