The length of disulfide bond-containing linkages impacts the oral absorption and antitumor activity of paclitaxel prodrug-loaded nanoemulsions.
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DOI: 10.1039/d1nr01359a
Abstract: The rational design of oral paclitaxel (PTX) preparations is still a challenge. Many studies focus on developing PTX-loaded nanoemulsions (NEs) for oral administration. Unfortunately, PTX has poor affinity with the commonly used oil phases, leading… read more here.
Keywords: disulfide bond; ptx; containing linkages; bond containing ... See more keywords