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Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra03761k
Abstract: Proteolysis targeting chimeras (PROTACs) represent an emerging class of compounds for innovative therapeutic application. Their bifunctional nature induces the formation of a ternary complex (target protein/PROTAC/E3 ligase) which allows target protein ubiquitination and subsequent proteasomal-dependent…
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Keywords:
containing linkers;
effect;
piperazine containing;
protonation ... See more keywords