Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain
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DOI: 10.1021/acsmedchemlett.2c00084
Abstract: Human African Trypanosomiasis (HAT) is a neglected tropical disease widespread in sub-Saharan Africa. Rhodesain, a cysteine protease of Trypanosoma brucei rhodesiense, has been identified as a valid target for the development of anti-HAT agents. Herein,… read more here.
Keywords: michael acceptors; bond containing; development; urea bond ... See more keywords