Microvesicles containing microRNA-21 secreted by proximal tubular epithelial cells are involved in renal interstitial fibrosis by activating AKT pathway.
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DOI: 10.26355/eurrev_201802_14297
Abstract: OBJECTIVE To investigate the role of microvesicles containing microRNA-21 in renal interstitial fibrosis and its possible mechanism. MATERIALS AND METHODS The renal interstitial fibrosis model was established by unilateral ureteral obstruction, and proximal tubule epithelial… read more here.
Keywords: interstitial fibrosis; fibrosis; containing microrna; microrna secreted ... See more keywords
Microvesicles containing microRNA-21 induce myocardial fibrosis via AKT pathway.
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DOI: 10.26355/eurrev_201807_15522
Abstract: OBJECTIVE To explore the role of microvesicles (MVs) containing microRNA-21 in myocardial fibrosis and their underlying mechanism. MATERIALS AND METHODS Myocardial ischemia rat model was first constructed for collecting myocardial tissues. Myocardial fibrosis-related indicators and… read more here.
Keywords: fibrosis; myocardial fibrosis; containing microrna; fibrosis via ... See more keywords