Isoxazole-containing 5' mRNA cap analogues as inhibitors of the translation initiation process.
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DOI: 10.1016/j.bioorg.2020.103583
Abstract: Herein we describe a synthesis of new isoxazole-containing 5' mRNA cap analogues via a cycloaddition reaction. The obtained analogues show a capability to inhibit cap-dependent translation in vitro and are characterized by a new binding… read more here.
Keywords: isoxazole containing; mrna cap; containing mrna; cap analogues ... See more keywords