Identification and preparation of selenium-containing peptides from selenium-enriched Pleurotus eryngii and their protective effect on lead-induced oxidative damage in NCTC1469 hepatocytes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12529
Abstract: BACKGROUND Lead (Pb) is a highly toxic and persistent substance that easily accumulates in living organisms, eliciting cellular toxicity and oxidative stress. Some selenium-containing proteins and peptides prepared from plant extracts are beneficial for protecting… read more here.
Keywords: selenium containing; selenium enriched; enriched pleurotus; induced oxidative ... See more keywords
Interaction Mechanism and Clustering among RGD Peptides and Integrins
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DOI: 10.1002/minf.201600069
Abstract: Peptides with an exposed arginine–glycine–aspartate (Arg–Gly–Asp, RGD) sequence targeting the integrin αVβ3 play an important role in targeted anticancer drug delivery. The interaction of multiple RGD‐containing peptides and two αVβ3 molecules was studied via MD… read more here.
Keywords: rgd containing; interaction mechanism; interaction; containing peptides ... See more keywords
Identification of β‐aminopyrrolidine containing peptides as β‐amyloid aggregation inhibitors for Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Peptide Science"
DOI: 10.1002/psc.3386
Abstract: Alzheimer's disease (AD) is caused by a series of events initiated by the production and aggregation of the amyloid β‐protein (Aβ). In the early stages of the disease, Aβ is released in a soluble form… read more here.
Keywords: identification aminopyrrolidine; aggregation; alzheimer disease; aminopyrrolidine containing ... See more keywords
Effects of tryptophan-containing peptides on angiotensin-converting enzyme activity and vessel tone ex vivo and in vivo
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DOI: 10.1007/s00394-016-1374-y
Abstract: PurposeOver-activation of the renin-angiotensin axis and worsening of vascular function are critical contributors to the development of hypertension. Therefore, inhibition of angiotensin-converting enzyme (ACE), a key factor of the renin-angiotensin axis, is a first line… read more here.
Keywords: vivo; tryptophan containing; vessel tone; containing peptides ... See more keywords
Cysteine-Containing Peptides Stimulate Monocyte Migration through NADPH-Oxidase Activation
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3766-2
Abstract: We analyzed migration of monocytes under the effect of apocinin (NADPH inhibitor) and PD98059 (blocker of extracellular MEK/ERK kinase involved in Nox4 oxidase-mediated migration of monocytes). Migration of monocytes stimulated by cysteine-containing peptides (fragments of… read more here.
Keywords: oxidase; migration; containing peptides; monocyte migration ... See more keywords
Arginine-Containing Peptides Derived from Walnut Protein Against Cognitive and Memory Impairment in Scopolamine-Induced Zebrafish: Design, Release, and Neuroprotection.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c05104
Abstract: The purpose of this study was to investigate the neuroprotective effect of Arg-containing peptides from walnut storage protein sequences in scopolamine-induced zebrafish and further to validate the potential neuroprotection of Arg-containing peptide enriched walnut hydrolysates… read more here.
Keywords: neuroprotection; arg containing; induced zebrafish; scopolamine induced ... See more keywords
Enriching Cysteine-Containing Peptides Using a Sulfhydryl-Reactive Alkylating Reagent with a Phosphonic Acid Group and Immobilized Metal Affinity Chromatography.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00806
Abstract: The reduction of disulfide bonds and their subsequent alkylation are commonplace in typical proteomics workflows. Here, we highlight a sulfhydryl-reactive alkylating reagent with a phosphonic acid group (iodoacetamido-LC-phosphonic acid, 6C-CysPAT) that facilitates the enrichment of… read more here.
Keywords: phosphonic acid; containing peptides; sulfhydryl reactive; reactive alkylating ... See more keywords
Structure–Activity Relationships of RGD-Containing Peptides in Integrin αvβ5-Mediated Cell Adhesion
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DOI: 10.1021/acsomega.2c06540
Abstract: The RGD motif is a cell adhesion sequence that binds to integrins, a receptor family for extracellular matrix proteins. We previously reported that the RGDX1X2 sequence, where X1X2 is VF or NY, is required for… read more here.
Keywords: adhesion; cell adhesion; containing peptides; mediated cell ... See more keywords
Genome Mining Reveals High Topological Diversity of ω-Ester Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b12076
Abstract: ω-Ester containing peptides (OEPs) are a family of ribosomally synthesized and post-translationally modified peptides (RiPPs) containing intramolecular ω-ester or ω-amide bonds. Although their distinct side-to-side connections may create considerable topological diversity of multicyclic peptides, it… read more here.
Keywords: atp grasp; ester; containing peptides; genome mining ... See more keywords
Perspectives of ruthenium(ii) polyazaaromatic photo-oxidizing complexes photoreactive towards tryptophan-containing peptides and derivatives.
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DOI: 10.1039/c7cc06542f
Abstract: RuII polyazaaromatic complexes have been studied with the aim of developing molecular tools for DNA and oligonucleotides. In this context, RuII-TAP (TAP = 1,4,5,8-tetraazaphenanthrene) complexes have been developed as specific photoreagents targeting the genetic material.… read more here.
Keywords: tap; photo oxidizing; photo; oxidizing complexes ... See more keywords
Continuous-flow processes for the S-alkynylation of cysteine-containing peptides and thioglycosides under catalyst-free, oxidant-free and mild conditions
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DOI: 10.1039/d1gc01937f
Abstract: Selective S-alkynylation of cysteine-containing peptides and 1-thioglycoside residues was developed using continuous flow. read more here.
Keywords: continuous flow; containing peptides; cysteine containing; alkynylation cysteine ... See more keywords