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Published in 2024 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.7753
Abstract: Structural modification is an advanced strategy to improve the biological activity of selected compounds and is effectively used to overcome the adverse properties of phytochemicals (e.g., curcumin), such as poor bioavailability and solubility, which limit…
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Keywords:
ferrocene containing;
analogs curcumin;
antioxidant activity;
containing pyrazole ... See more keywords
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Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.129960
Abstract: Abstract A series of diazotised aniline and aniline derivative compounds were reacted with solution of malononitrile in pyridine at 0–5 °C were obtained 1a-1m compounds. Then 4-arylazo-3,5-diamino-1H-pyrazole (2a-2m) derivatives were synthesized by coupling arylazo malononitrile…
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Keywords:
novel heterocyclic;
dyes containing;
spectroscopy;
containing pyrazole ... See more keywords
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Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c05674
Abstract: Sulfonamide derivatives have been widely used for pesticide research in recent years. Herein, 1,3,4-oxadiazole sulfonamide derivatives containing a pyrazole structure were synthesized, and their structure-activity relationship was studied. Bioactivity tests showed the remarkable efficacy of…
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Keywords:
pyrazole structures;
derivatives containing;
sulfonamide derivatives;
oxadiazole sulfonamide ... See more keywords
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Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c11375
Abstract: Paeonol is the main active ingredient in the Chinese medicinal herb peony root bark. To discover biorational natural product-based fungicides, 25 paeonol derivatives (5a-y) containing a pyrazole ring were designed and synthesized by ingeniously introducing…
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Keywords:
oomycete antifungal;
paeonol derivatives;
derivatives containing;
anti oomycete ... See more keywords
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Published in 2019 at "Molecules"
DOI: 10.3390/molecules24071311
Abstract: To develop new antibacterial agents, a series of novel triazole-containing pyrazole ester derivatives were designed and synthesized and their biological activities were evaluated as potential topoisomerase II inhibitors. Compound 4d exhibited the most potent antibacterial…
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Keywords:
antibacterial agents;
topoisomerase;
pyrazole ester;
containing pyrazole ... See more keywords
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Published in 2018 at "Indian Journal of Pharmaceutical Sciences"
DOI: 10.4172/pharmaceutical-sciences.1000351
Abstract: In the present communication synthesis of pyrazole-containing dihydropyrimidinone motifs (4a-o) and their antimicrobial activity and cytotoxicity were reported. The newly synthesized compounds were characterized using infrared, proton nuclear magnetic resonance, carbon-13 nuclear magnetic resonance and…
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Keywords:
antimicrobial activity;
activity fluorine;
containing pyrazole;
synthesis antimicrobial ... See more keywords