Real‐world outcomes with bortezomib‐containing regimens and lenalidomide plus dexamethasone for the treatment of transplant‐ineligible multiple myeloma: a multi‐institutional report from the Canadian Myeloma Research Group database
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DOI: 10.1111/bjh.17350
Abstract: Bortezomib‐containing regimens (BCRs) represented standard, first‐line therapy for transplant‐ineligible multiple myeloma (TIMM) in Canada until the introduction of lenalidomide and low‐dose dexamethasone (Ld). However, little comparative data exist to inform the selection of regimens. We… read more here.
Keywords: transplant ineligible; containing regimens; myeloma; ineligible multiple ... See more keywords
Twenty-four-week interim outcomes of bedaquiline-containing regimens in treatment of adolescents with rifampicin-resistant tuberculosis: A retrospective cohort study in China.
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DOI: 10.1111/jpc.15672
Abstract: AIM To evaluate the 24-week interim outcomes of bedaquiline-containing regimens in the treatment of adolescents with rifampicin-resistant tuberculosis (RR-TB) in China. METHODS Adolescents with RR-TB from two hospitals were included in this retrospective study. All… read more here.
Keywords: interim outcomes; containing regimens; treatment; week interim ... See more keywords
In a Pinch: Cefiderocol for CRAB Infections
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DOI: 10.1128/aac.00065-22
Abstract: Carbapenem-resistant Acinetobacter baumannii (CRAB) can cause significant infections with limited treatment options available. Falcone et al. (https://doi.org/10.1128/aac.02142-21) describe a single-center retrospective study comparing clinical outcomes among patients with CRAB infections treated with cefiderocol-containing versus colistin-containing… read more here.
Keywords: containing regimens; cefiderocol crab; cefiderocol containing; pinch cefiderocol ... See more keywords
Assessing Pretomanid for Tuberculosis (APT), a Randomized Phase 2 Trial of Pretomanid-containing Regimens for Drug-sensitive TB: 12-Week Results.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202208-1475oc
Abstract: RATIONALE Pretomanid is a new nitroimidazole with proven treatment-shortening efficacy in drug-resistant tuberculosis. Pretomanid-rifamycin-pyrazinamide combinations are potent in mice but have not been tested clinically. Rifampicin, but not rifabutin, reduces pretomanid exposures. OBJECTIVE Evaluate the… read more here.
Keywords: containing regimens; arm arm; arm; tuberculosis ... See more keywords
Clinical and Cost Comparison Evaluation of Inpatient Versus Outpatient Administration of EPOCH-Containing Regimens in Non-Hodgkin Lymphoma
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DOI: 10.1177/0897190016659210
Abstract: Background: Etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin (EPOCH)-containing regimens are frequently utilized in non-Hodgkin’s lymphoma, however, the incidence of febrile neutropenia (FN) in patients receiving inpatient versus outpatient EPOCH has not been described. Additionally, no comparisons… read more here.
Keywords: administration; containing regimens; cost; non hodgkin ... See more keywords
Acquisition of double mutation in gyrA caused high resistance to sitafloxacin in Helicobacter pylori after unsuccessful eradication with sitafloxacin-containing regimens
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DOI: 10.1177/2050640617737215
Abstract: Background and aim Although sitafloxacin (STFX)-containing regimens are effective rescue treatments for Helicobacter pylori infection, prevalence of fluoroquinolone resistance in H. pylori has increased rapidly worldwide. The change in resistance levels and gyrA mutations, a… read more here.
Keywords: eradication; containing regimens; pylori unsuccessful; stfx containing ... See more keywords
A Retrospective Analysis of the Efficacy and Safety of Orelabrutinib-Containing Regimens in Marginal Zone Lymphoma
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DOI: 10.1182/blood-2024-198795
Abstract: Background and Objective: Marginal zone lymphoma (MZL) is a prevalent indolent B-cell non-Hodgkin lymphoma (NHL) that remains incurable with standard therapy. The associated treatment toxicity further constrains therapeutic options. Orelabrutinib, a novel BTK inhibitor, is… read more here.
Keywords: treatment; rate; orelabrutinib containing; efficacy ... See more keywords
Increased C-Reactive Protein Level Is Associated with Poor Prognosis in Patients with Follicular Lymphoma Treated with Rituximab-Containing Regimens
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DOI: 10.1182/blood.v130.suppl_1.4067.4067
Abstract: Introduction: C-reactive protein (CRP) is a useful inflammatory marker in clinical practice. It is a prognostic factor in several types of tumors, including diffuse large B cell lymphoma (DLBCL) and extranodal natural killer/T-cell lymphoma, nasal… read more here.
Keywords: elevated crp; containing regimens; associated poor; rituximab containing ... See more keywords
Impact of different antiretroviral therapy regimens on bone mineral density in people living with HIV: a retrospective and longitudinal study in China
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DOI: 10.1186/s12879-024-10299-y
Abstract: HIV infection and antiretroviral therapy (ART) are associated with bone loss of people living with HIV (PLWH), but limited studies exist on the impacts of ART regimens on bone mineral density (BMD) in China. This… read more here.
Keywords: tdf 3tc; 3tc efv; taf containing; dtg containing ... See more keywords
Efficacy and safety of Sofosbuvir-containing regimens in patients co-infected with chronic hepatitis C virus and human immunodeficiency virus: a meta-analysis
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DOI: 10.1186/s12985-018-0934-6
Abstract: BackgroundThe treatment of hepatitis C virus (HCV) in HCV/human immunodeficiency virus (HIV) co-infected patients remains complex. This present meta-analysis evaluated the efficacy and safety of Sofosbuvir (SOF) for treatment in HCV/HIV co-infected patients using the… read more here.
Keywords: patients infected; containing regimens; efficacy safety; analysis ... See more keywords
Effectiveness and Safety of Rifaximin-Containing Regimens for Helicobacter pylori Eradication: Systematic Review – Are They Potential Eradication Regimens?
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DOI: 10.2147/idr.s371131
Abstract: Background Rifaximin, a rifamycin antibiotic, is widely used to treat infectious diarrhea but not commonly used in H. pylori eradication. With its potential advantages of the agent, some studies were conducted on this topic. The… read more here.
Keywords: containing regimens; pylori eradication; effectiveness safety; eradication ... See more keywords