Diverse synthetic approach for sulfur and nitrogen-containing spiroheterocycles from dimedone and their pharmacological evaluation
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DOI: 10.1080/00397911.2019.1650281
Abstract: Abstract Novel spiro(3-hydroxy-5,5-dimethyl)-1,5’-(2’-substituated[1,3,4]-oxadiazole/thiadiazolo[3,2-c] thiazolines and 3-hydroxy-5,5-dimethyl-spiro[cyclohex-2-ene-thiazolo/thiazino[3,2-b]-s-tetrazine were prepared from previously reported hydrazone, semicarbazone, carbazone, and spiro-s-tetrazine intermediates derived from dimedone precursor. All the newly synthesized heterocycles have been characterized by analytical and spectral (1H NMR… read more here.
Keywords: approach sulfur; containing spiroheterocycles; sulfur nitrogen; nitrogen containing ... See more keywords