Actin Assembly around the Shigella-Containing Vacuole Promotes Successful Infection
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DOI: 10.1016/j.celrep.2020.107638
Abstract: Summary The enteroinvasive bacterium Shigella flexneri forces its uptake into non-phagocytic host cells through the translocation of T3SS effectors that subvert the actin cytoskeleton. Here, we report de novo actin polymerization after cellular entry around… read more here.
Keywords: actin assembly; containing vacuole; actin; infection ... See more keywords
Dictyostelium lacking the single atlastin homolog Sey1 shows aberrant ER architecture, proteolytic processes and expansion of the Legionella‐containing vacuole
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DOI: 10.1111/cmi.13318
Abstract: Dictyostelium discoideum Sey1 is the single ortholog of mammalian atlastin 1–3 (ATL1‐3), which are large homodimeric GTPases mediating homotypic fusion of endoplasmic reticulum (ER) tubules. In this study, we generated a D. discoideum mutant strain… read more here.
Keywords: containing vacuole; legionella containing; sey1; dictyostelium ... See more keywords
Proximity labelling reveals VPS13C as a regulator of Salmonella-containing vacuole fission
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DOI: 10.1371/journal.ppat.1013507
Abstract: Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative intracellular bacterial pathogen that grows within a specialized membrane-bound compartment known as the Salmonella-containing vacuole (SCV). The molecular composition and regulatory mechanisms governing SCV dynamics remain… read more here.
Keywords: salmonella containing; scv; salmonella; containing vacuole ... See more keywords