New validated spectrofluorimetric protocol for colistin assay through condensation with 2,2-dihydroxyindan-1,3-dione: application to content uniformity testing
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DOI: 10.1039/d2ra04259b
Abstract: A new, cost-effective and sensitive spectroscopic assay for the quantification of Colistin Sulfate (CS) and its prodrug colistimethate sodium (CMS) has been developed and validated. The validated technique depends on the condensation of the studied… read more here.
Keywords: uniformity testing; condensation; dihydroxyindan dione; content uniformity ... See more keywords
Two green spectrofluorimetric methods for the assay of atomoxetine hydrochloride in pure form and commercial capsules with application to content uniformity testing
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DOI: 10.1098/rsos.230010
Abstract: Atomoxetine hydrochloride (ATX) is a potent and non-stimulant drug which was approved for the treatment of attention-deficit hyperactivity disorder. Owing to its importance, two green, simple and validated spectrofluorimetric methods were developed for its sensitive… read more here.
Keywords: spectrofluorimetric methods; pure; atomoxetine hydrochloride; two green ... See more keywords
An investigation into the effects of excipient particle size, blending techniques and processing parameters on the homogeneity and content uniformity of a blend containing low-dose model drug
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DOI: 10.1371/journal.pone.0178772
Abstract: Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending… read more here.
Keywords: topography; content uniformity; particle size; uniformity ... See more keywords