A Cocktail of Two Chelators Is Not Better than One Ligand in Excess to Halt Cu,Zn-(Amyloid-β)-Induced ROS Production in the Context of Alzheimer's Disease.
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DOI: 10.1021/acs.inorgchem.5c03352
Abstract: In this study, we demonstrate that an excess of the nonselective chelator EDTA can effectively extract both copper(II) and zinc(II) from the amyloid-β (Aβ) peptide and halt Cu(Aβ)-catalyzed ROS production in the context of Alzheimer's… read more here.
Keywords: production context; alzheimer disease; context alzheimer; halt ... See more keywords