Context is everything: extrinsic signalling and gain-of-function p53 mutants.
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DOI: 10.1038/s41420-020-0251-x
Abstract: The TP53 genomic locus is a target of mutational events in at least half of cancers. Despite several decades of study, a full consensus on the relevance of the acquisition of p53 gain-of-function missense mutants… read more here.
Keywords: p53; gain function; context everything; p53 mutants ... See more keywords