Context fear learning and renewal of extinguished fear are dissociated in juvenile female rats.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental psychobiology"
DOI: 10.1002/dev.21888
Abstract: Extinction is the decrease in emotion to a cue that was previously associated with an emotionally significant event. It involves repeated presentation of the cue without any consequences. In adult animals, extinguished fear to a… read more here.
Keywords: fear; renewal; cue; context fear ... See more keywords
Hippocampal damage causes retrograde but not anterograde memory loss for context fear discrimination in rats
Sign Up to like & getrecommendations! Published in 2017 at "Hippocampus"
DOI: 10.1002/hipo.22759
Abstract: There is a substantial body of evidence that the hippocampus (HPC) plays and essential role in context discrimination in rodents. Studies reporting anterograde amnesia (AA) used repeated, alternating, distributed conditioning and extinction sessions to measure… read more here.
Keywords: fear discrimination; context fear; hpc; damage ... See more keywords
Extinction and discrimination in a Bayesian model of context fear conditioning (BaconX)
Sign Up to like & getrecommendations! Published in 2021 at "Hippocampus"
DOI: 10.1002/hipo.23298
Abstract: The extinction of contextual fear is commonly an essential requirement for successful exposure therapy for fear disorders. However, experimental work on extinction of contextual fear is limited, and there little or no directly relevant theoretical… read more here.
Keywords: fear; fear conditioning; extinction; context fear ... See more keywords
Amnesia for context fear is caused by widespread disruption of hippocampal activity
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2020.107295
Abstract: The hippocampus plays an essential role in the formation and retrieval of episodic memories in humans and contextual memories in animals. However, amnesia is not always observed when this structure is compromised. To address this… read more here.
Keywords: caused widespread; hippocampal activity; retrieval; context fear ... See more keywords
The effect of acute nicotine administration on human delay cued and context fear conditioning.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental and clinical psychopharmacology"
DOI: 10.1037/pha0000592
Abstract: Nicotine has been shown to facilitate hippocampal-dependent context fear conditioning (FC), but not hippocampal-independent delay cued fear conditioning. Studies examining the effects of nicotine on learned fear have been exclusively limited to nonhumans. The present… read more here.
Keywords: delay cued; cued context; fear; context fear ... See more keywords
Context Fear Conditioning in Down Syndrome Mouse Models: Effects of Trisomic Gene Content, Age, Sex and Genetic Background
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12101528
Abstract: Down syndrome (DS), trisomy of the long arm of human chromosome 21 (Hsa21), is the most common genetic cause of intellectual disability (ID). Currently, there are no effective pharmacotherapies. The success of clinical trials to… read more here.
Keywords: mouse models; age; fear conditioning; context fear ... See more keywords