Glutamatergic Projections from the Entorhinal Cortex to Dorsal Dentate Gyrus Mediate Context-Induced Reinstatement of Heroin Seeking
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychopharmacology"
DOI: 10.1038/npp.2017.14
Abstract: Reexposure to the context associated with heroin intake provokes relapse to drug taking after abstinence. The dorsal dentate gyrus (dDG) and entorhinal cortex (EC) have been implicated in contextual memory processing, but the underlying circuit… read more here.
Keywords: context; reinstatement heroin; heroin seeking; context induced ... See more keywords
Context‐induced relapse to cocaine seeking after punishment‐imposed abstinence is associated with activation of cortical and subcortical brain regions
Sign Up to like & getrecommendations! Published in 2018 at "Addiction Biology"
DOI: 10.1111/adb.12527
Abstract: We recently developed a rat model of context‐induced relapse to alcohol seeking after punishment‐imposed abstinence to mimic relapse after self‐imposed abstinence due to adverse consequences of drug use. Here, we determined the model's generality to… read more here.
Keywords: relapse; imposed abstinence; context induced; induced relapse ... See more keywords
Role of mu, but not delta or kappa, opioid receptors in context‐induced reinstatement of oxycodone seeking
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.13955
Abstract: Relapse to non‐medical use of prescription opioids often occurs after exposure to places previously associated with drug use. Here, we describe a rat model of context‐induced reinstatement of oxycodone seeking after repeated cycles of drug… read more here.
Keywords: reinstatement; oxycodone seeking; reinstatement oxycodone; context induced ... See more keywords