Articles with "contextual reprogramming" as a keyword



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Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers

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Published in 2021 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-021-03132-6

Abstract: Background Adoptive transfer of chimeric antigen receptor (CAR)-engineered T cells combined with checkpoint inhibition may prevent T cell exhaustion and improve clinical outcomes. However, the approach is limited by cumulative costs and toxicities. Methods To… read more here.

Keywords: cells treatment; contextual reprogramming; reprogramming car; car cells ... See more keywords