Technoeconomic Optimization of Continuous Crystallization for Three Active Pharmaceutical Ingredients: Cyclosporine, Paracetamol, and Aliskiren
Sign Up to like & getrecommendations! Published in 2018 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.8b00679
Abstract: Mixed suspension, mixed product removal (MSMPR) crystallizers are widely implemented for the continuous crystallization of active pharmaceutical ingredients (APIs), allowing enhanced efficiency, flexibility, and product quality compared to currently dominant batch crystallizer designs. Establishing cost-effective… read more here.
Keywords: crystallization; active pharmaceutical; optimization; cyclosporine paracetamol ... See more keywords
Fluidic Oscillator as a Continuous Crystallizer: Feasibility Evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.9b04637
Abstract: Crystallization is an important separation unit operation accounting for nearly 90% of organic molecules in the pharmaceutical and fine chemical industries. Recently, continuous crystallization was demonstrated to have several advantages over the conventional batch crystallization… read more here.
Keywords: continuous crystallizer; oscillator continuous; fluidic oscillator; crystallization ... See more keywords