Optimized Continuous Multicolumn Chromatography Enables Increased Productivities and Cost Savings by Employing More Columns
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DOI: 10.1002/biot.201800179
Abstract: The advantages of continuous chromatography with respect to increased capacity are well established. However, the impact of different loading scenarios and total number of columns on the process economics has not been addressed. Here four… read more here.
Keywords: chromatography; multicolumn chromatography; process; continuous multicolumn ... See more keywords
Scale-up of continuous multicolumn chromatography for the protein a capture step: From bench to clinical manufacturing.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2018.07.022
Abstract: The awareness about implementing continuous processing for biopharmaceutical products has significantly increased throughout the recent years not only at developmental scale but also for phase I supply in clinical trial manufacturing. In this study, we… read more here.
Keywords: protein; chromatography; manufacturing; continuous multicolumn ... See more keywords