Identifying overarching excipient properties towards an in-depth understanding of process and product performance for continuous twin-screw wet granulation.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.02.028
Abstract: The overall objective of this work is to understand how excipient characteristics influence the process and product performance for a continuous twin-screw wet granulation process. The knowledge gained through this study is intended to be… read more here.
Keywords: product performance; process product; performance continuous; process ... See more keywords
Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.04.055
Abstract: In this study, the influence of key process variables (screw speed, throughput and liquid to solid (L/S) ratio) of a continuous twin screw wet granulation (TSWG) was investigated using a central composite face-centered (CCF) experimental… read more here.
Keywords: design; twin screw; screw wet; process ... See more keywords
Native starch as in situ binder for continuous twin screw wet granulation.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118760
Abstract: The use of native starch as in situ binder in a continuous twin screw wet granulation process was studied. Gelatinization of pea starch occurred in the barrel of the granulator using a poorly soluble excipient… read more here.
Keywords: native starch; situ binder; binder; continuous twin ... See more keywords