Moisture-Adaptive Contractile Biopolymer-Derived Fibers for Wound Healing Promotion.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202300589
Abstract: The advancement in thermosensitive active hydrogels has opened promising opportunities to dynamic full-thickness skin wound healing. However, conventional hydrogels lack breathability to avoid wound infection and cannot adapt to wounds with different shapes due to… read more here.
Keywords: wound healing; contraction; adaptive contractile; contractile ... See more keywords
Cross-education: effects of age on rapid and maximal voluntary contractile characteristics in males
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-019-04123-8
Abstract: PurposeThe purpose of this study was to determine the effect of age on the cross-education of rapid and maximal contractile properties for the knee extensors.MethodsYoung (n = 10; age = 21.1 ± 1.7 years) and older (n = 10; age = 65.3 ± 8.3 years) males performed unilateral isokinetic… read more here.
Keywords: contractile; age; rapid maximal; cross education ... See more keywords
Bioprinted gelatin hydrogel platform promotes smooth muscle cell contractile phenotype maintenance
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical Microdevices"
DOI: 10.1007/s10544-018-0274-8
Abstract: Three dimensional (3D) bioprinting has been proposed as a method for fabricating tissue engineered small diameter vascular prostheses. This technique not only involves constructing the structural features to obtain a desired pattern but the morphology… read more here.
Keywords: gelatin hydrogel; smooth muscle; contractile; contractile phenotype ... See more keywords
Pirfenidone attenuates the profibrotic contractile phenotype of differentiated human dermal myofibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.10.177
Abstract: Dysregulated wound healing after burn injury frequently results in debilitating hypertrophic scarring and contractures. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts via transforming growth factor beta 1 (TGF-β1). During wound… read more here.
Keywords: contractile; pirfenidone attenuates; profibrotic contractile; contractile phenotype ... See more keywords
Mechanical Response of Fibrous Materials to Local Contractile Loads
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2017.11.2022
Abstract: When cells contract or migrate within a three-dimensional fibrous matrix, they pull on the fibers surrounding them, generating displacements in the fibrous network. As there is no clear constitutive relationship for fibrous materials, the connections… read more here.
Keywords: local contractile; contractile; fibrous materials; mechanical response ... See more keywords
Theoretical Analysis of Stress Distribution and Cell Polarization Surrounding a Model Wound.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical journal"
DOI: 10.1016/j.bpj.2018.06.011
Abstract: A growing amount of experimental evidence shows that the local elastic field acting on cells governs their spatial organization and polarity in a tissue. Interestingly, experiments on wound healing reveal a universal formation of thick… read more here.
Keywords: contractile; actomyosin; model; stress ... See more keywords
The effects of doxorubicin on cardiac calcium homeostasis and contractile function.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2022.01.001
Abstract: Cancer is one of the leading causes of death globally and the number of cancer deaths is rising as a result of increased longevity. Doxorubicin (DOX) is one of the most effective anti-neoplastic drugs used… read more here.
Keywords: contractile; contractile function; calcium; homeostasis ... See more keywords
Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR–v-ATPase axis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2021.101293
Abstract: Objective The diabetic heart is characterized by extensive lipid accumulation which often leads to cardiac contractile dysfunction. The underlying mechanism involves a pivotal role for vacuolar-type H+-ATPase (v-ATPase, functioning as endosomal/lysosomal proton pump). Specifically, lipid… read more here.
Keywords: heart; contractile; atpase; contractile dysfunction ... See more keywords
Amalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09225-x
Abstract: We evaluated the cardioprotective effect of Amalaki Rasayana (AR), a rejuvenating Ayurvedic drug prepared from Phyllanthusemblica fruits in the reversal of remodeling changes in pressure overload left ventricular cardiac hypertrophy (LVH) and age-associated cardiac dysfunction… read more here.
Keywords: contractile; cardiac function; amalaki rasayana; drug ... See more keywords
The Long Non-coding RNA Carmn is a Critical Regulator of Gastrointestinal Smooth Muscle Contractile Function and Motility.
Sign Up to like & getrecommendations! Published in 2023 at "Gastroenterology"
DOI: 10.1053/j.gastro.2023.03.229
Abstract: BACKGROUND & AIMS Visceral smooth muscle cells (SMCs) are an integral component of the gastrointestinal (GI) tract that regulate GI motility. SMC contraction is regulated by post-translational signaling and the state of differentiation. Impaired SMC… read more here.
Keywords: carmn; rna; muscle; motility ... See more keywords
Thermal Stability of Contractile Proteins in Bat Wing Muscles Explains Differences in Temperature Dependence of Whole-Muscle Shortening Velocity
Sign Up to like & getrecommendations! Published in 2022 at "Physiological and Biochemical Zoology"
DOI: 10.1086/722449
Abstract: Muscle contractile properties are dependent on temperature: cooler temperatures generally slow contractile rates. Contraction and relaxation are driven by underlying biochemical systems, which are inherently sensitive to temperature. Carollia perspicillata, a small Neotropical bat, experiences… read more here.
Keywords: wing muscles; muscle; temperature; shortening velocity ... See more keywords