Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload
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DOI: 10.1038/s41551-018-0280-4
Abstract: The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and recapitulation of disease pathologies. Here, using a cardiac tissue… read more here.
Keywords: mechanical overload; mybpc3 deficiency; contractile deficits; tissue ... See more keywords