High throughput screening system for engineered cardiac tissues
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1177688
Abstract: Introduction: Three dimensional engineered cardiac tissues (3D ECTs) have become indispensable as in vitro models to assess drug cardiotoxicity, a leading cause of failure in pharmaceutical development. A current bottleneck is the relatively low throughput… read more here.
Keywords: system; contractile force; engineered cardiac; throughput screening ... See more keywords
Connexin 43 suppression enhances contractile force in human iPSC-derived cardiac tissues
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2025.1615953
Abstract: Connexin 43 (Cx43) plays a crucial role in maintaining synchronous contraction in the heart. However, it remains unclear whether Cx43 directly influences the contractile force and synchrony of entire cardiac tissues. Previously, we successfully developed… read more here.
Keywords: derived cardiac; cardiac tissues; force; contractile force ... See more keywords
Contractile force assessment methods for in vitro skeletal muscle tissues
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77204
Abstract: Over the last few years, there has been growing interest in measuring the contractile force (CF) of engineered muscle tissues to evaluate their functionality. However, there are still no standards available for selecting the most… read more here.
Keywords: contractile force; engineered muscle; muscle; muscle tissues ... See more keywords