Bioprinted gelatin hydrogel platform promotes smooth muscle cell contractile phenotype maintenance
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical Microdevices"
DOI: 10.1007/s10544-018-0274-8
Abstract: Three dimensional (3D) bioprinting has been proposed as a method for fabricating tissue engineered small diameter vascular prostheses. This technique not only involves constructing the structural features to obtain a desired pattern but the morphology… read more here.
Keywords: gelatin hydrogel; smooth muscle; contractile; contractile phenotype ... See more keywords
Pirfenidone attenuates the profibrotic contractile phenotype of differentiated human dermal myofibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.10.177
Abstract: Dysregulated wound healing after burn injury frequently results in debilitating hypertrophic scarring and contractures. Myofibroblasts, the main effector cells for dermal fibrosis, develop from normal fibroblasts via transforming growth factor beta 1 (TGF-β1). During wound… read more here.
Keywords: contractile; pirfenidone attenuates; profibrotic contractile; contractile phenotype ... See more keywords
Vascular smooth muscle remodeling in health and disease.
Sign Up to like & getrecommendations! Published in 2020 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2020-0399
Abstract: In blood vessels, vascular smooth muscle cells (VSMCs) generally exist in two major phenotypes: contractile and non-contractile (synthetic). The contractile phenotype is predominant and includes quiescent or differentiated VSMCs, which function as the regulators of… read more here.
Keywords: phenotype; vascular smooth; contractile phenotype; smooth muscle ... See more keywords
Abstract 1055: Atxn2 Inhibition Enhances The Contractile Phenotype Of Vascular Smooth Muscle Cells
Sign Up to like & getrecommendations! Published in 2024 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvb.44.suppl_1.1055
Abstract: Introduction: Phenotype switching of vascular smooth muscle cells (VSMC) between their synthetic and differentiated contractile state is a critical player in controlling the stability of atherosclerotic plaque. Hundreds of genes associated with coronary artery disease… read more here.
Keywords: atxn2 inhibition; smooth muscle; vsmc; contractile phenotype ... See more keywords
Epithelial Cells Induce a Cyclo‐Oxygenase‐1‐Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2016-0427oc
Abstract: &NA; Airway smooth muscle cells (ASMCs) are phenotypically regulated to exist in either a proliferative or a contractile state. However, the influence of other airway structural cell types on ASMC phenotype is largely unknown. Although… read more here.
Keywords: phenotype; epithelial cells; smooth muscle; contractile phenotype ... See more keywords
Evaluation of contractile phenotype in airway smooth muscle cells isolated from endobronchial biopsy and tissue specimens from horses.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of veterinary research"
DOI: 10.2460/ajvr.78.3.359
Abstract: OBJECTIVE To develop a method to maintain the initial phenotype of airway smooth muscle (ASM) cells isolated from equine endobronchial biopsy specimens in long-term cell culture. SAMPLE Endobronchial tissue specimens (8 to 10/horse) collected from… read more here.
Keywords: phenotype; biopsy; asm cells; contractile phenotype ... See more keywords