Sliding filament and fixed filament mechanisms contribute to ring tension in the cytokinetic contractile ring
Sign Up to like & getrecommendations! Published in 2019 at "Cytoskeleton"
DOI: 10.1002/cm.21558
Abstract: A fundamental challenge in cell biology is to understand how cells generate actomyosinâbased contractile force. Here we study the actomyosin contractile ring that divides cells during cytokinesis and generates tension by a mechanism that remains… read more here.
Keywords: mechanism; fixed filament; contractile ring; tension ... See more keywords
Building the contractile ring from the ground up: a lesson in perseverance and scientific creativity
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Reviews"
DOI: 10.1007/s12551-018-0482-8
Abstract: This contribution to the Festschrift for Professor Thomas (Tom) D. Pollard focuses on his work on the elucidation of the protein organization within the cytokinetic nodes, protein assemblies, precursors to the contractile ring. In particular,… read more here.
Keywords: research; ground lesson; lesson perseverance; ring ground ... See more keywords
Imp2p forms actin-dependent clusters and imparts stiffness to the contractile ring
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e22-06-0221
Abstract: The contractile ring must anchor to the plasma membrane and cell wall to transmit its tension. F-BAR domain containing proteins including Imp2p and Cdc15p in fission yeast are likely candidate anchoring proteins based on their… read more here.
Keywords: actin dependent; imp2p forms; forms actin; contractile ring ... See more keywords
Preprint Highlight: Building the cytokinetic contractile ring in an early embryo: initiation as clusters of myosin II, anillin and septin, and visualization of a septin filament network.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology of the cell"
DOI: 10.1091/mbc.p22-03-1001
Abstract: Cytokinesis is driven by a contractile ring whose key components are well-defined. Yet how they are organized and how the contractile ring assembles and constricts, remain unclear. This study combines confocal and super resolution imaging… read more here.
Keywords: contractile ring; septin filament; anillin; contractile ... See more keywords