Stiffening Matrix Induces Age‐Mediated Microvascular Phenotype Through Increased Cell Contractility and Destabilization of Adherens Junctions
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201483
Abstract: Aging is a major risk factor in microvascular dysfunction and disease development, but the underlying mechanism remains largely unknown. As a result, age‐mediated changes in the mechanical properties of tissue collagen have gained interest as… read more here.
Keywords: cell; matrix; age; contractility ... See more keywords
Beneficial effects of lipidic extracts of saladette tomato pomace and Serenoa repens on prostate and bladder health in obese male Wistar rats.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8308
Abstract: BACKGROUND Obesity is associated with increased risk of a number of serious medical conditions, including urological disorders. This study investigated the effect of lipidic extracts of saladette tomato pomace (STP) and Serenoa repens (SR) on… read more here.
Keywords: bladder; lipidic extracts; saladette tomato; prostate bladder ... See more keywords
Increased myocardial contractility identifies patients with decompensated cirrhosis requiring liver transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Liver Transplantation"
DOI: 10.1002/lt.24846
Abstract: Late allocation of organs for transplant impairs post–liver transplantation (LT) survival. Cardiac dysfunction, especially diastolic and autonomic dysfunction, is frequent and plays an important role in the prognosis of patients with cirrhosis. However, the role… read more here.
Keywords: identifies patients; increased myocardial; myocardial contractility; liver transplantation ... See more keywords
Validation of three-dimensional echocardiographic principal strain analysis for assessing left ventricular contractility: An animal study.
Sign Up to like & getrecommendations! Published in 2019 at "Medical physics"
DOI: 10.1002/mp.13509
Abstract: PURPOSE The three-dimensional (3D) principal strain represents the major direction and magnitude of the deformation by its definition and can be measured using 3D echocardiography. We aimed to validate 3D echocardiographic left ventricular (LV) global… read more here.
Keywords: three dimensional; volume; contractility; principal strain ... See more keywords
Right ventricular function in pulmonary (arterial) hypertension
Sign Up to like & getrecommendations! Published in 2019 at "Herz"
DOI: 10.1007/s00059-019-4815-6
Abstract: The right ventricle (RV) is the main determinant of prognosis in pulmonary hypertension. Adaptation and maladaptation of the RV are of crucial importance. In the course of disease, RV contractility increases through changes in muscle… read more here.
Keywords: die; function; maladaptation; der ... See more keywords
Letter to the editor: does estrogen deprivation affect pelvic floor muscle contractility?
Sign Up to like & getrecommendations! Published in 2019 at "International Urogynecology Journal"
DOI: 10.1007/s00192-019-04086-6
Abstract: To the Editor, We read with interest the recent article “Does estrogen deprivation affect pelvic floor muscle contractility?” by Hans Peter Dietz and co-authors [1]. This article concluded that estrogen deprivation is unlikely to be… read more here.
Keywords: contractility; pelvic floor; muscle contractility; pop ... See more keywords
Structure and function of resistance arteries from BB-creatine kinase and ubiquitous Mt-creatine kinase double knockout mice
Sign Up to like & getrecommendations! Published in 2020 at "Amino Acids"
DOI: 10.1007/s00726-020-02872-x
Abstract: Increasing evidence indicates that the enzyme creatine kinase (CK) is intimately involved in microvascular contractility. The mitochondrial isoenzyme catalyses phosphocreatine synthesis from ATP, while cytoplasmic CK, predominantly the BB isoenzyme in vascular tissue, is tightly… read more here.
Keywords: resistance arteries; function; kinase; creatine kinase ... See more keywords
Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-021-07299-4
Abstract: β-Adrenergic receptors (βAR) are essential targets for the treatment of heart failure (HF); however, chronic use of βAR agonists as positive inotropes to increase contractility in a Gs protein-dependent manner is associated with increased mortality.… read more here.
Keywords: icl1 mediated; contractility; icl1; cardiomyocyte contractility ... See more keywords
The myometrial contractility during late pregnancy in dairy cows, in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2017.04.001
Abstract: This study aimed to investigate the in vitro contractility of the myometrium and its relationship to the blood concentrations of estradiol-17β (E2β), progesterone (P4), 15-keto-13,14-dihydro-PGF2α (PGFM) and ionised calcium (Ca2+) prior to tissue harvest in… read more here.
Keywords: contractility late; myometrial contractility; late pregnancy; contractility ... See more keywords
Alterations in the relative abundance of the vasoactive intestinal peptide receptors (VPAC1 and VPAC2) and functions in uterine contractility during inflammation.
Sign Up to like & getrecommendations! Published in 2020 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2020.106680
Abstract: Vasoactive intestinal peptide (VIP) receptor (VPAC1, VPAC2) abundances in the myometrium and functions in the regulation of inflamed uterine contractility in pigs were studied. In the CON group with gilts, only laparotomy was performed. The… read more here.
Keywords: vip; treatment; contractility; receptor ... See more keywords
Machine-learning-based quality control of contractility of cultured human-induced pluripotent stem-cell-derived cardiomyocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.141
Abstract: The precise and early assessment of cardiotoxicity is fundamental to bring forward novel drug candidates to the pharmaceutical market and to avoid their withdrawal from the market. Recent preclinical studies have attempted to use human-induced… read more here.
Keywords: human induced; pluripotent stem; induced pluripotent; contractility ... See more keywords