Kynureninase contributes to the pathogenesis of psoriasis through pro-inflammatory effect.
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DOI: 10.1002/jcp.30587
Abstract: Kynureninase (KYNU) is a key enzyme in the tryptophan metabolism pathway with elevated expression in psoriatic lesions relative to normal skin. However, whether KYNU contributes to the pathogenesis of psoriasis remains unknown. We sought to… read more here.
Keywords: kynureninase; kynu; skin; psoriasis ... See more keywords
Mitophagy Contributes to the Pathogenesis of Inflammatory Diseases
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DOI: 10.1007/s10753-018-0835-2
Abstract: Mitophagy is a metabolic process to remove excessive or damaged mitochondria in eukaryotic cells. It is well-known that mitochondria are one of the major sources of reactive oxygen species (ROS). Mitochondrial ROS and damage-associated molecular… read more here.
Keywords: pathogenesis inflammatory; mitophagy contributes; inflammatory diseases; contributes pathogenesis ... See more keywords