Articles with "contributes sorafenib" as a keyword



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CCL22 signaling contributes to sorafenib resistance in hepatitis B virus-associated hepatocellular carcinoma.

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Published in 2020 at "Pharmacological research"

DOI: 10.1016/j.phrs.2020.104800

Abstract: The HBV-initiated hepatocellular carcinoma (HCC) frequently develops from or accompanies long-term chronic hepatitis, inflammation, and cirrhosis, and has a poor prognosis. Sorafenib, an orally active multi-kinase inhibitor, currently the most common approved drug for first-line… read more here.

Keywords: hepatocellular carcinoma; ccl22 signaling; ccl22; sorafenib resistance ... See more keywords