Articles with "contributes tumorigenesis" as a keyword



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WTAP contributes to the tumorigenesis of osteosarcoma via modulating ALB in an m6A‐dependent manner

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Published in 2023 at "Environmental Toxicology"

DOI: 10.1002/tox.23780

Abstract: Osteosarcoma (OS) is a prevalent bone malignancy mainly occurred in adolescents. WTAP/N6‐methyladenosine (m6A) modification is confirmed to be involved in OS progression. This study is conducted to bring some novel insights to the action mechanism… read more here.

Keywords: wtap; contributes tumorigenesis; wtap contributes; tumorigenesis osteosarcoma ... See more keywords
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PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-11019-w

Abstract: Unfolded protein response (UPR) is an adaptive mechanism that aims at restoring ER homeostasis under severe environmental stress. Malignant cells are resistant to environmental stress, which is largely due to an activated UPR. However, the… read more here.

Keywords: ire1; environmental stress; stress; prkcsh contributes ... See more keywords