Articles with "contribution molecular" as a keyword



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Relative contribution of molecular mechanisms to cumulative ligand-mediated downregulation of GRα.

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Published in 2022 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2022.02.102

Abstract: Central to the pharmacological use of glucocorticoids (GCs) is the availability of the glucocorticoid receptor alpha (GRα). However, chronic GC therapy often results in the ligand-mediated downregulation of the GRα, and the subsequent development of… read more here.

Keywords: mediated downregulation; relative contribution; contribution molecular; molecular mechanisms ... See more keywords