Glial Dysfunction and Its Contribution to the Pathogenesis of the Neuronal Ceroid Lipofuscinoses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.886567
Abstract: While significant efforts have been made in developing pre-clinical treatments for the neuronal ceroid lipofuscinoses (NCLs), many challenges still remain to bring children with NCLs a cure. Devising effective therapeutic strategies for the NCLs will… read more here.
Keywords: ceroid lipofuscinoses; glial dysfunction; neuronal ceroid; contribution pathogenesis ... See more keywords
Mitochondrial Aconitase and Its Contribution to the Pathogenesis of Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25189950
Abstract: This survey reviews modern ideas on the structure and functions of mitochondrial and cytosolic aconitase isoenzymes in eukaryotes. Cumulative experimental evidence about mitochondrial aconitases (Aco2) as one of the main targets of reactive oxygen and… read more here.
Keywords: contribution pathogenesis; neurodegenerative diseases; mitochondrial aconitase; aconitase contribution ... See more keywords