Remote control of γc expression by arginine methylation
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0240-x
Abstract: Arginine methylation is a post-translational modification that controls the abundance of γc cytokine receptor on mature T cells by a post-transcriptional mechanism. read more here.
Keywords: remote control; methylation; arginine methylation; expression arginine ... See more keywords
Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytes
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-001521
Abstract: Background The inhibitory functions triggered by the programmed cell death-1 (PD-1) receptor following binding to its ligand (PD-L1) protect healthy organs from cytotoxic T cells, and neutralize antitumor T cell attack. Antibody-based therapies to block… read more here.
Keywords: kinase limits; expression; control expression; diacylglycerol kinase ... See more keywords