Control for population stratification in genetic association studies based on GWAS summary statistics
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DOI: 10.1002/gepi.22493
Abstract: Over the past years, genome‐wide association studies (GWAS) have generated a wealth of new information. Summary data from many GWAS are now publicly available, promoting the development of many statistical methods for association studies based… read more here.
Keywords: population; control population; population stratification; association studies ... See more keywords
A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis
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DOI: 10.1371/journal.pone.0213350
Abstract: Whole-genome sequencing is a promising approach for human autosomal dominant disease studies. However, the vast number of genetic variants observed by this method constitutes a challenge when trying to identify the causal variants. This is… read more here.
Keywords: control population; number; disease; geographically matched ... See more keywords
Behavioral Patterns of Depression Patients and Control Population
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DOI: 10.3390/ijerph19159506
Abstract: Behavioral and multifactorial factors, such as psychological, nutritional, dental pathology, and physical activity habits, are factors that control depression. The objective of the present study was to analyze the differences in the behavioral, psychological, nutritional,… read more here.
Keywords: depression; physical activity; pathology; group ... See more keywords